Is it possible to know who the true Antichrist is from the Bible or can we only speculate on who the man of sin is? What has been the consistent testimony from the early church to about 200 years ago? Is the Pope of Rome that man of sin and son of perdition, or is it some man to come in the future?
“There is no other head of the Church but the Lord Jesus Christ. Nor can the Pope of Rome, in any sense, be head thereof; but is that Antichrist, that man of sin, and son of perdition, that exalts himself, in the Church, against Christ and all that is called God.”
-The Westminster Confession of Faith, Chapter 25:6